Astroblastome de l'Enfant à propos d’un cas

Authors

  • ERRAAD Ibtissam
  • EL HIMRI Sami
  • BENTALEB Daouad

DOI:

https://doi.org/10.55715/jaim.v17i2.777

Abstract

Introduction: Astroblastoma is a rare primitive glial tumor found in children and young adults, preferentially located supratentorially. The aim of this article is to highlight the radiological features of this rare tumor on CT and MRI and to emphasize the challenges encountered during diagnosis.

Case Report : We present the case of a 13-year-old girl diagnosed with astroblastoma, which manifested as intracranial hypertension syndrome and visual disturbances, and was confirmed through histopathological and molecular studies.

Discussion : Astroblastoma is a glial tumor that is rarely reported in the literature. Clinical and radiological signs are non-specific and may mimic other differential diagnoses. Treatment is based on surgery and adjuvant radiochemotherapy.

Conclusion : Although it is rare, astroblastoma should be included in the differential diagnosis of supratentorial tumors in children and young adults.Given itssometimes aggressive nature,early management and a multidisciplinary approach are important.

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References

Hammas N, Senhaji N, Alaoui Lamrani MY, Bennis S, Chaoui EM, El Fatemi H, et al. Astroblastoma – a rare and challenging tumor: a case report and review of the literature. J Med Case Reports. 2018 Dec;12:102. DOI: 10.1186/s13256-018-1623-1

Louis DN, Perry A, Wesseling P, Brat DJ, Cree IA, Figarella-Branger D et al. The 2021 WHO Classification of Tumors of the Centtral Nervous System: a summary. Neuro Oncol. 2021 Jun 29 ;23:1231-51. DOI: 10.1093/neuonc/noab106

Cunningham DA, Lowe LH, Shao L, Acosta NR. Neuroradiologic characteristics of astroblastoma and systematic review of the literature: 2 new cases and 125 cases reported in 59 publications. Pediatr Radiol. 2016; 46:1301-08. DOI: 10.1007/s00247-016-3607x

Yapıcıer Ö, Demir MK, Özdamarlar U,Özdamarlar U, Kılıç D, Akakın A, Kılıç T. Posterior fossa astroblastoma in a child: a case report and a review of the literature. Childs Nerv Syst. 2019 Jul;35:1251-55. DOI: 10.1007/s00381-019-04113-3

Bell JW, Osborn AG, Salzman KL, Blaser SI, Jones BV, Chin SS. Neuroradiologic characteristics of astroblastoma. Neuroradiology.2007 Mar;49:203-9. DOI: 10.1007/s00234-006-0182-0

Sprenger F, Da Silva EB, Cavalcanti MS, Alemda Teixeira BC. Radiology-Pathology and Surgical Correlation in Astroblastoma.AJNR AmJNeuroradiol.2023 Apr;44:390-95. DOI: 10.3174/ajnr.A7824

Cuoco JA. DO,Williams S, Klein BJ, Borowicz VM, Ho H, Stump MS, Rogers CM. Astroblastoma With a Novel YAP1::BEND2 Fusion: A Case Report. Journal of Pediatric Hematology/Oncology. 2024 Jul 1;46:e313-e316. DOI:10.1097/MPH.0000000000002885

Mhatre R, Sugur HS, Nandeesh BN, Chickabasaviah Y, Saini J, Santosh V. MN1 rearrangement in astroblastoma: study of eight cases and review of literature. Brain Tumor Pathol. 2019 Jul;36:112-120. Doi: 10.1007/s10014-019-00346-x. Epub 2019 May 20. PMID: 31111274.

Fu L, Lao IW, Huang L, Ou L, Yuan L, Li Z, Li S, Hu W, Xi S. Spinal Cord Astroblastoma With EWSR1-BEND2 Fusion in Female Patients : A Report of Four Cases From China and a Comprehensive Literature Review. Am J Surg Pathol. 2024 Nov 1;48(11):1372-80. DOI: 10.1097/PAS.0000000000002298

Published

2025-06-10

How to Cite

ERRAAD Ibtissam, EL HIMRI Sami, & BENTALEB Daouad. (2025). Astroblastome de l’Enfant à propos d’un cas . Journal Africain D Imagerie Médicale (J Afr Imag Méd) Journal Officiel De La Société De Radiologie d’Afrique Noire Francophone (SRANF), 17(2), 113–118. https://doi.org/10.55715/jaim.v17i2.777